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Targeting lung cancer cells with MUC1 aptamer-functionalized PLA-PEG nanocarriers

MUC1 aptamer-functionalized PLA-PEG nanocarriers at various w/w ratios (polymer to doxorubicin weight ratio) were prepared by a double emulsion method. Physiochemical properties, encapsulation efficiency (EE), loading content (LC) and in vitro release kinetics of DOX were assessed. Furthermore, cyto...

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Detalles Bibliográficos
Autores principales: Shahrad, Shima, Rajabi, Mohammad, Javadi, Hamidreza, Karimi Zarchi, Ali Akbar, Darvishi, Mohammad Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933396/
https://www.ncbi.nlm.nih.gov/pubmed/35304550
http://dx.doi.org/10.1038/s41598-022-08759-z