Transcriptomic analysis of human sensory neurons in painful diabetic neuropathy reveals inflammation and neuronal loss

Pathological sensations caused by peripheral painful neuropathy occurring in Type 2 diabetes mellitus (T2DM) are often described as ‘sharp’ and ‘burning’ and are commonly spontaneous in origin. Proposed etiologies implicate dysfunction of nociceptive sensory neurons in dorsal root ganglia (DRG) indu...

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Detalles Bibliográficos
Autores principales: Hall, Bradford E., Macdonald, Emma, Cassidy, Margaret, Yun, Sijung, Sapio, Matthew R., Ray, Pradipta, Doty, Megan, Nara, Pranavi, Burton, Michael D., Shiers, Stephanie, Ray-Chaudhury, Abhik, Mannes, Andrew J., Price, Theodore J., Iadarola, Michael J., Kulkarni, Ashok B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933403/
https://www.ncbi.nlm.nih.gov/pubmed/35304484
http://dx.doi.org/10.1038/s41598-022-08100-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933403/
https://www.ncbi.nlm.nih.gov/pubmed/35304484
http://dx.doi.org/10.1038/s41598-022-08100-8

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