Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis

Most tumours are thought to arise through oncogenic cell generation followed by additional mutations. How a new oncogenic cell primes tumorigenesis by acquiring additional mutations remains unclear. We show that an additional TP53 mutation stimulates primary tumorigenesis by switching oncogene-induc...

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Detalles Bibliográficos
Autores principales: Haraoka, Yukinari, Akieda, Yuki, Nagai, Yuri, Mogi, Chihiro, Ishitani, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933407/
https://www.ncbi.nlm.nih.gov/pubmed/35304872
http://dx.doi.org/10.1038/s41467-022-29061-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933407/
https://www.ncbi.nlm.nih.gov/pubmed/35304872
http://dx.doi.org/10.1038/s41467-022-29061-6

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