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The interplay of additivity, dominance, and epistasis on fitness in a diploid yeast cross
In diploid species, genetic loci can show additive, dominance, and epistatic effects. To characterize the contributions of these different types of genetic effects to heritable traits, we use a double barcoding system to generate and phenotype a panel of ~200,000 diploid yeast strains that can be pa...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933436/ https://www.ncbi.nlm.nih.gov/pubmed/35304450 http://dx.doi.org/10.1038/s41467-022-29111-z |