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The interplay of additivity, dominance, and epistasis on fitness in a diploid yeast cross

In diploid species, genetic loci can show additive, dominance, and epistatic effects. To characterize the contributions of these different types of genetic effects to heritable traits, we use a double barcoding system to generate and phenotype a panel of ~200,000 diploid yeast strains that can be pa...

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Detalles Bibliográficos
Autores principales: Matsui, Takeshi, Mullis, Martin N., Roy, Kevin R., Hale, Joseph J., Schell, Rachel, Levy, Sasha F., Ehrenreich, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933436/
https://www.ncbi.nlm.nih.gov/pubmed/35304450
http://dx.doi.org/10.1038/s41467-022-29111-z