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A high-throughput real-time PCR tissue-of-origin test to distinguish blood from lymphoblastoid cell line DNA for (epi)genomic studies

Lymphoblastoid cell lines (LCLs) derive from blood infected in vitro by Epstein–Barr virus and were used in several genetic, transcriptomic and epigenomic studies. Although few changes were shown between LCL and blood genotypes (SNPs) validating their use in genetics, more were highlighted for other...

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Detalles Bibliográficos
Autores principales: Hardy, Lise M., Bouyacoub, Yosra, Daunay, Antoine, Sahbatou, Mourad, Baudrin, Laura G., Gressin, Laetitia, Touvier, Mathilde, Blanché, Hélène, Deleuze, Jean-François, How-Kit, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933453/
https://www.ncbi.nlm.nih.gov/pubmed/35304543
http://dx.doi.org/10.1038/s41598-022-08663-6