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WTAP-mediated m(6)A modification of lncRNA NORAD promotes intervertebral disc degeneration
N6-methyladenosine (m(6)A) is the most prevalent RNA modification at the posttranscriptional level and involved in various diseases and cellular processes. However, the underlying mechanism of m(6)A regulation in intervertebral disc degeneration (IVDD) remains elusive. Here, we show that methylation...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933458/ https://www.ncbi.nlm.nih.gov/pubmed/35304463 http://dx.doi.org/10.1038/s41467-022-28990-6 |