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l-Carnitine reduces reactive oxygen species/endoplasmic reticulum stress and maintains mitochondrial function during autophagy-mediated cell apoptosis in perfluorooctanesulfonate-treated renal tubular cells

We previously reported that perfluorooctanesulfonate (PFOS) causes autophagy-induced apoptosis in renal tubular cells (RTCs) through a mechanism dependent on reactive oxygen species (ROS)/extracellular signal-regulated kinase. This study extended our findings and determined the therapeutic potency o...

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Detalles Bibliográficos
Autores principales: Lee, Yuan-Chii Gladys, Chou, Hsiu-Chu, Chen, Yen-Ting, Tung, Szu-Yu, Ko, Tsui-Ling, Buyandelger, Batsaikhan, Wen, Li-Li, Juan, Shu-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933466/
https://www.ncbi.nlm.nih.gov/pubmed/35304586
http://dx.doi.org/10.1038/s41598-022-08771-3