Optimization of an O(2)-balanced bioartificial pancreas for type 1 diabetes using statistical design of experiment

A bioartificial pancreas (BAP) encapsulating high pancreatic islets concentration is a promising alternative for type 1 diabetes therapy. However, the main limitation of this approach is O(2) supply, especially until graft neovascularization. Here, we described a methodology to design an optimal O(2...

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Detalles Bibliográficos
Autores principales: Mouré, Anne, Bekir, Sawsen, Bacou, Elodie, Pruvost, Quentin, Haurogné, Karine, Allard, Marie, De Beaurepaire, Laurence, Bosch, Steffi, Riochet, David, Gauthier, Olivier, Blancho, Gilles, Soulillou, Jean-Paul, Poncelet, Denis, Mignot, Grégoire, Courcoux, Philippe, Jegou, Dominique, Bach, Jean-Marie, Mosser, Mathilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933496/
https://www.ncbi.nlm.nih.gov/pubmed/35304495
http://dx.doi.org/10.1038/s41598-022-07887-w

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