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Loops, topologically associating domains, compartments, and territories are elastic and robust to dramatic nuclear volume swelling

Layers of genome organization are becoming increasingly better characterized, but less is known about how these structures respond to perturbation or shape changes. Low-salt swelling of isolated chromatin fibers or nuclei has been used for decades to investigate the structural properties of chromati...

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Detalles Bibliográficos
Autores principales: Sanders, Jacob T., Golloshi, Rosela, Das, Priyojit, Xu, Yang, Terry, Peyton H., Nash, Darrian G., Dekker, Job, McCord, Rachel Patton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933507/
https://www.ncbi.nlm.nih.gov/pubmed/35304523
http://dx.doi.org/10.1038/s41598-022-08602-5