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Protocol for computationally evaluating the loss of stoichiometry and coordinated expression of proteins
Dysregulation of the transcriptional or translational machinery can alter the stoichiometry of multiprotein complexes and occurs in natural processes such as aging. Loss of stoichiometry has been shown to alter protein complex functions. We provide a protocol and associated code that use omics data...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933523/ https://www.ncbi.nlm.nih.gov/pubmed/35313706 http://dx.doi.org/10.1016/j.xpro.2022.101182 |