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Protocol for computationally evaluating the loss of stoichiometry and coordinated expression of proteins

Dysregulation of the transcriptional or translational machinery can alter the stoichiometry of multiprotein complexes and occurs in natural processes such as aging. Loss of stoichiometry has been shown to alter protein complex functions. We provide a protocol and associated code that use omics data...

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Detalles Bibliográficos
Autores principales: Hinz, Stefan, Todhunter, Michael E., LaBarge, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933523/
https://www.ncbi.nlm.nih.gov/pubmed/35313706
http://dx.doi.org/10.1016/j.xpro.2022.101182

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