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Obesity induces resistance to central action of BMP8B through a mechanism involving the BBSome

OBJECTIVE: Bone morphogenetic protein 8B (BMP8B) plays a major role in the regulation of energy homeostasis by modulating brown adipose tissue (BAT) thermogenesis and white adipose tissue (WAT) browning. Here, we investigated whether BMP8B's role in metabolism is affected by obesity and the pos...

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Detalles Bibliográficos
Autores principales: Rial-Pensado, Eva, Freire-Agulleiro, Oscar, Ríos, Marcos, Guo, Deng Fu, Contreras, Cristina, Seoane-Collazo, Patricia, Tovar, Sulay, Nogueiras, Rubén, Diéguez, Carlos, Rahmouni, Kamal, López, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933534/
https://www.ncbi.nlm.nih.gov/pubmed/35218946
http://dx.doi.org/10.1016/j.molmet.2022.101465