Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids

Patient-derived tumor organoids (PDOs) are a highly promising preclinical model that recapitulates the histology, gene expression, and drug response of the donor patient tumor. Currently, PDO culture relies on basement-membrane extract (BME), which suffers from batch-to-batch variability, the presen...

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Detalles Bibliográficos
Autores principales: Prince, Elisabeth, Cruickshank, Jennifer, Ba-Alawi, Wail, Hodgson, Kelsey, Haight, Jillian, Tobin, Chantal, Wakeman, Andrew, Avoulov, Alona, Topolskaia, Valentina, Elliott, Mitchell J., McGuigan, Alison P., Berman, Hal K., Haibe-Kains, Benjamin, Cescon, David W., Kumacheva, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933543/
https://www.ncbi.nlm.nih.gov/pubmed/35304464
http://dx.doi.org/10.1038/s41467-022-28788-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933543/
https://www.ncbi.nlm.nih.gov/pubmed/35304464
http://dx.doi.org/10.1038/s41467-022-28788-6

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