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Determinants of IGF-II influencing stability, receptor binding and activation

Insulin like growth factor II (IGF-II) is involved in metabolic and mitogenic signalling in mammalian cells and plays important roles in normal fetal development and postnatal growth. It is structurally similar to insulin and binds not only with high affinity to the type 1 insulin-like growth factor...

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Detalles Bibliográficos
Autores principales: Blyth, Andrew, Ortiz, Michael, Merriman, Allanah, Delaine, Carlie, Forbes, Briony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933565/
https://www.ncbi.nlm.nih.gov/pubmed/35304516
http://dx.doi.org/10.1038/s41598-022-08467-8