Elucidation of the conformational dynamics and assembly of Argonaute–RNA complexes by distinct yet coordinated actions of the supplementary microRNA

Argonaute (AGO) proteins, the core of RNA-induced silencing complex, are guided by microRNAs (miRNAs) to recognize target RNA for repression. The miRNA–target RNA recognition forms initially through pairing at the seed region while the additional supplementary pairing can enhance target recognition...

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Detalles Bibliográficos
Autores principales: Zhuang, Haiming, Fan, Xiaohua, Ji, Dong, Wang, Yuanhao, Fan, Jigang, Li, Mingyu, Ni, Duan, Lu, Shaoyong, Li, Xiaolong, Chai, Zongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933676/
https://www.ncbi.nlm.nih.gov/pubmed/35356544
http://dx.doi.org/10.1016/j.csbj.2022.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933676/
https://www.ncbi.nlm.nih.gov/pubmed/35356544
http://dx.doi.org/10.1016/j.csbj.2022.03.001

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