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Involvement of the BDNF–TrkB–KCC2 pathway in neuropathic pain after brachial plexus avulsion

INTRODUCTION: Brachial plexus avulsion significantly increased brain‐derived neurotrophic factor (BDNF) release in the spinal cord. Here we investigated the involvement of the BDNF–TrkB–KCC2 pathway in neuropathic pain caused by BPA injury. We hypothesized that activation of BDNF–TrkB may inhibit ne...

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Detalles Bibliográficos
Autores principales: Zhao, Shuo, Wang, Fengyu, Wang, Li, Xu, Yali, Lv, Li, Duan, Wenxu, Bai, Runze, Meng, Zhao, Shao, Xinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933754/
https://www.ncbi.nlm.nih.gov/pubmed/35106976
http://dx.doi.org/10.1002/brb3.2464