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A novel inhibitor of monooxygenase reversed the activity of tetracyclines against tet(X3)/tet(X4)-positive bacteria

BACKGROUND: Tigecycline is one of the few last-resort antibiotics for the treatment of carbapenem-resistant Enterobacteriaceae infection, the incidence of which has been rapidly increasing. However, the emergence and spread of tigecycline resistance genes tet(X) (including tet(X3) and tet(X4)) has l...

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Detalles Bibliográficos
Autores principales: Xu, Lei, Zhou, Yonglin, Niu, Sen, Liu, Zhiying, Zou, Yinuo, Yang, Yanan, Feng, Haihua, Liu, Dejun, Niu, Xiaodi, Deng, Xuming, Wang, Yang, Wang, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933826/
https://www.ncbi.nlm.nih.gov/pubmed/35306337
http://dx.doi.org/10.1016/j.ebiom.2022.103943