FLAMBE: A kinetic fluorescence polarization assay to study activation of monomeric BAX

BAX activation techniques are crucial to studying the intrinsic pathway of apoptosis— thousands of pro-apoptotic signals converge on BAX activation. Current methodologies are predominantly limited to membrane permeabilization studies, which assess endpoint functionality of oligomeric BAX, but overlo...

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Detalles Bibliográficos
Autores principales: Mohammed, Jarvier N., Gelles, Jesse D., Chipuk, Jerry Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933840/
https://www.ncbi.nlm.nih.gov/pubmed/35313708
http://dx.doi.org/10.1016/j.xpro.2022.101252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933840/
https://www.ncbi.nlm.nih.gov/pubmed/35313708
http://dx.doi.org/10.1016/j.xpro.2022.101252

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