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FLAMBE: A kinetic fluorescence polarization assay to study activation of monomeric BAX
BAX activation techniques are crucial to studying the intrinsic pathway of apoptosis— thousands of pro-apoptotic signals converge on BAX activation. Current methodologies are predominantly limited to membrane permeabilization studies, which assess endpoint functionality of oligomeric BAX, but overlo...
Autores principales: | Mohammed, Jarvier N., Gelles, Jesse D., Chipuk, Jerry Edward |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933840/ https://www.ncbi.nlm.nih.gov/pubmed/35313708 http://dx.doi.org/10.1016/j.xpro.2022.101252 |
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