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SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease

COVID-19 and the renin-angiotensin system (RAS) are linked by angiotensin-converting enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a SARS-CoV-2 receptor. Functional ACE1/ACE2 gene polymorphisms may lead to the imbalance between ACE/ACE2 ratio and thus generating RAS imbalance that...

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Detalles Bibliográficos
Autores principales: Alimoradi, Nahid, Sharqi, Moein, Firouzabadi, Dena, Sadeghi, Mohammad Moein, Moezzi, Mohammad Iman, Firouzabadi, Negar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934128/
https://www.ncbi.nlm.nih.gov/pubmed/35305693
http://dx.doi.org/10.1186/s12985-022-01782-6