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A method for assaying peptide: N-glycanase/N-glycanase 1 activities in crude extracts using an N-glycosylated cyclopeptide

Cytosolic peptide: N-glycanase (PNGase; NGLY1), an enzyme responsible for de-glycosylation of N-glycans on glycoproteins, is known to play pivotal roles in a variety of biological processes. In 2012, NGLY1 deficiency, a rare genetic disorder, was reported and since then, more than 100 patients have...

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Detalles Bibliográficos
Autores principales: Hirayama, Hiroto, Tachida, Yuriko, Seino, Junichi, Suzuki, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934141/
https://www.ncbi.nlm.nih.gov/pubmed/34939090
http://dx.doi.org/10.1093/glycob/cwab115