Mesenchymal Stem Cell-Secreted TGF-β1 Restores Treg/Th17 Skewing Induced by Lipopolysaccharide and Hypoxia Challenge via miR-155 Suppression

BACKGROUND: Regulatory T cell (Treg)/T helper (Th) 17 skewing is important in the development of acute respiratory distress syndrome (ARDS). Immunomodulatory effects of mesenchymal stem cell- (MSC-) secreted transforming growth factor- (TGF-) β1 on CD4(+) T cells are environment-sensitive and lack d...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Ming, Zhang, Xiwen, Chen, Jianxiao, Liu, Feng, Xu, Jingyuan, Xie, Jianfeng, Yang, Yi, Yu, Weiping, Qiu, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934213/
https://www.ncbi.nlm.nih.gov/pubmed/35313652
http://dx.doi.org/10.1155/2022/5522828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934213/
https://www.ncbi.nlm.nih.gov/pubmed/35313652
http://dx.doi.org/10.1155/2022/5522828

Ejemplares similares