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Improvement of Lipotoxicity-Induced Islet β Cellular Insulin Secretion Disorder by Osteocalcin

BACKGROUND: Osteocalcin (OCN) has been proved to be closely related with the development of type 2 diabetes mellitus (T2DM). We aimed to study if OCN could improve the disorder of islet cell caused by lipotoxicity. METHODS: Alizarin red staining was used to investigate the mineralization. Western bl...

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Detalles Bibliográficos
Autores principales: Zhang, Yafang, Li, Ling, Zhang, Yongze, Yan, Sunjie, Huang, Lingning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934231/
https://www.ncbi.nlm.nih.gov/pubmed/35313683
http://dx.doi.org/10.1155/2022/3025538