A role for the periplasmic adaptor protein AcrA in vetting substrate access to the RND efflux transporter AcrB

Tripartite resistance-nodulation-division (RND) efflux pumps, such as AcrAB-TolC of Salmonella Typhimurium, contribute to antibiotic resistance and comprise an inner membrane RND-transporter, an outer membrane factor, and a periplasmic adaptor protein (PAP). The role of the PAP in the assembly and a...

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Detalles Bibliográficos
Autores principales: Alav, Ilyas, Bavro, Vassiliy N., Blair, Jessica M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934357/
https://www.ncbi.nlm.nih.gov/pubmed/35306531
http://dx.doi.org/10.1038/s41598-022-08903-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934357/
https://www.ncbi.nlm.nih.gov/pubmed/35306531
http://dx.doi.org/10.1038/s41598-022-08903-9

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