Affinity2Vec: drug-target binding affinity prediction through representation learning, graph mining, and machine learning

Drug-target interaction (DTI) prediction plays a crucial role in drug repositioning and virtual drug screening. Most DTI prediction methods cast the problem as a binary classification task to predict if interactions exist or as a regression task to predict continuous values that indicate a drug'...

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Detalles Bibliográficos
Autores principales: Thafar, Maha A., Alshahrani, Mona, Albaradei, Somayah, Gojobori, Takashi, Essack, Magbubah, Gao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934358/
https://www.ncbi.nlm.nih.gov/pubmed/35306525
http://dx.doi.org/10.1038/s41598-022-08787-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934358/
https://www.ncbi.nlm.nih.gov/pubmed/35306525
http://dx.doi.org/10.1038/s41598-022-08787-9

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