The Abcc6a Knockout Zebrafish Model as a Novel Tool for Drug Screening for Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a multisystem ectopic mineralization disorder caused by pathogenic variants in the ABCC6 gene. Though complications of the disease can be treated, PXE itself remains currently intractable. A strategy for rapid and cost-effective discovery of therapeutic drugs would...

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Detalles Bibliográficos
Autores principales: Van Gils, M., Willaert, A., Coucke, P. J., Vanakker, O. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934400/
https://www.ncbi.nlm.nih.gov/pubmed/35317004
http://dx.doi.org/10.3389/fphar.2022.822143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934400/
https://www.ncbi.nlm.nih.gov/pubmed/35317004
http://dx.doi.org/10.3389/fphar.2022.822143

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