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Strategies and Considerations for Improving Recombinant Antibody Production and Quality in Chinese Hamster Ovary Cells

Recombinant antibodies are rapidly developing therapeutic agents; approximately 40 novel antibody molecules enter clinical trials each year, most of which are produced from Chinese hamster ovary (CHO) cells. However, one of the major bottlenecks restricting the development of antibody drugs is how t...

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Detalles Bibliográficos
Autores principales: Zhang, Jun-He, Shan, Lin-Lin, Liang, Fan, Du, Chen-Yang, Li, Jing-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934426/
https://www.ncbi.nlm.nih.gov/pubmed/35316944
http://dx.doi.org/10.3389/fbioe.2022.856049