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Strategies and Considerations for Improving Recombinant Antibody Production and Quality in Chinese Hamster Ovary Cells
Recombinant antibodies are rapidly developing therapeutic agents; approximately 40 novel antibody molecules enter clinical trials each year, most of which are produced from Chinese hamster ovary (CHO) cells. However, one of the major bottlenecks restricting the development of antibody drugs is how t...
Autores principales: | Zhang, Jun-He, Shan, Lin-Lin, Liang, Fan, Du, Chen-Yang, Li, Jing-Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934426/ https://www.ncbi.nlm.nih.gov/pubmed/35316944 http://dx.doi.org/10.3389/fbioe.2022.856049 |
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