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Triamcinolone acetonide-loaded nanoparticles encapsulated by CD90(+) MCSs-derived microvesicles drive anti-inflammatory properties and promote cartilage regeneration after osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a highly prevalent human degenerative joint disorder that has long plagued patients. Glucocorticoid injection into the intra-articular (IA) cavity provides potential short-term analgesia and anti-inflammatory effects, but long-term IA injections cause loss of carti...

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Detalles Bibliográficos
Autores principales: Li, Yuanlong, Tu, Qingqiang, Xie, Dongmei, Chen, Shurui, Gao, Kai, Xu, Xiaochun, Zhang, Ziji, Mei, Xifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934450/
https://www.ncbi.nlm.nih.gov/pubmed/35305656
http://dx.doi.org/10.1186/s12951-022-01367-z