Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury

BACKGROUND: Peripheral nerve injuries are accompanied by inflammatory reactions, over-activation of which may hinder recovery. Among pro-inflammatory pathways, inflammasomes are one of the most potent, leading to release of active IL-1β. Our aim was to understand how inflammasomes participate in cen...

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Detalles Bibliográficos
Autores principales: Molnár, Kinga, Nógrádi, Bernát, Kristóf, Rebeka, Mészáros, Ádám, Pajer, Krisztián, Siklós, László, Nógrádi, Antal, Wilhelm, Imola, Krizbai, István A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934511/
https://www.ncbi.nlm.nih.gov/pubmed/35305649
http://dx.doi.org/10.1186/s12974-022-02427-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934511/
https://www.ncbi.nlm.nih.gov/pubmed/35305649
http://dx.doi.org/10.1186/s12974-022-02427-9

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