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Mechanisms of mitochondrial promoter recognition in humans and other mammalian species

Recognition of mammalian mitochondrial promoters requires the concerted action of mitochondrial RNA polymerase (mtRNAP) and transcription initiation factors TFAM and TFB2M. In this work, we found that transcript slippage results in heterogeneity of the human mitochondrial transcripts in vivo and in...

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Detalles Bibliográficos
Autores principales: Zamudio-Ochoa, Angelica, Morozov, Yaroslav I, Sarfallah, Azadeh, Anikin, Michael, Temiakov, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934621/
https://www.ncbi.nlm.nih.gov/pubmed/35191499
http://dx.doi.org/10.1093/nar/gkac103