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RAD51 protects against nonconservative DNA double-strand break repair through a nonenzymatic function

Selection of the appropriate DNA double-strand break (DSB) repair pathway is decisive for genetic stability. It is proposed to act according to two steps: 1-canonical nonhomologous end-joining (C-NHEJ) versus resection that generates single-stranded DNA (ssDNA) stretches; 2-on ssDNA, gene conversion...

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Detalles Bibliográficos
Autores principales: So, Ayeong, Dardillac, Elodie, Muhammad, Ali, Chailleux, Catherine, Sesma-Sanz, Laura, Ragu, Sandrine, Le Cam, Eric, Canitrot, Yvan, Masson, Jean Yves, Dupaigne, Pauline, Lopez, Bernard S, Guirouilh-Barbat, Josée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934640/
https://www.ncbi.nlm.nih.gov/pubmed/35137208
http://dx.doi.org/10.1093/nar/gkac073