Discovery of potent and versatile CRISPR–Cas9 inhibitors engineered for chemically controllable genome editing

Anti-CRISPR (Acr) proteins are encoded by many mobile genetic elements (MGEs) such as phages and plasmids to combat CRISPR–Cas adaptive immune systems employed by prokaryotes, which provide powerful tools for CRISPR–Cas-based applications. Here, we discovered nine distinct type II-A anti-CRISPR (Acr...

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Detalles Bibliográficos
Autores principales: Song, Guoxu, Zhang, Fei, Tian, Chunhong, Gao, Xing, Zhu, Xiaoxiao, Fan, Dongdong, Tian, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934645/
https://www.ncbi.nlm.nih.gov/pubmed/35188577
http://dx.doi.org/10.1093/nar/gkac099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934645/
https://www.ncbi.nlm.nih.gov/pubmed/35188577
http://dx.doi.org/10.1093/nar/gkac099

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