The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling

Biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) and their recycling after splicing require numerous assembly/recycling factors whose modes of action are often poorly understood. The intrinsically disordered TSSC4 protein has been identified as a nuclear-localized U5 snRNP and U4...

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Detalles Bibliográficos
Autores principales: Bergfort, Alexandra, Hilal, Tarek, Kuropka, Benno, Ilik, İbrahim Avşar, Weber, Gert, Aktaş, Tuğçe, Freund, Christian, Wahl, Markus C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934646/
https://www.ncbi.nlm.nih.gov/pubmed/35188580
http://dx.doi.org/10.1093/nar/gkac087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934646/
https://www.ncbi.nlm.nih.gov/pubmed/35188580
http://dx.doi.org/10.1093/nar/gkac087

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