The MukB-topoisomerase IV interaction mutually suppresses their catalytic activities

The bacterial condensin MukB and the cellular chromosomal decatenase, topoisomerase IV interact and this interaction is required for proper condensation and topological ordering of the chromosome. Here, we show that Topo IV stimulates MukB DNA condensation by stabilizing loops in DNA: MukB alone can...

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Detalles Bibliográficos
Autores principales: Kumar, Rupesh, Bahng, Soon, Marians, Kenneth J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934648/
https://www.ncbi.nlm.nih.gov/pubmed/34747485
http://dx.doi.org/10.1093/nar/gkab1027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934648/
https://www.ncbi.nlm.nih.gov/pubmed/34747485
http://dx.doi.org/10.1093/nar/gkab1027

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