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The MukB-topoisomerase IV interaction mutually suppresses their catalytic activities
The bacterial condensin MukB and the cellular chromosomal decatenase, topoisomerase IV interact and this interaction is required for proper condensation and topological ordering of the chromosome. Here, we show that Topo IV stimulates MukB DNA condensation by stabilizing loops in DNA: MukB alone can...
Autores principales: | Kumar, Rupesh, Bahng, Soon, Marians, Kenneth J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934648/ https://www.ncbi.nlm.nih.gov/pubmed/34747485 http://dx.doi.org/10.1093/nar/gkab1027 |
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