Grouped-seq for integrated phenotypic and transcriptomic screening of patient-derived tumor organoids

Patient-derived tumor organoids (PDOs) have emerged as a reliable in vitro model for drug discovery. However, RNA sequencing-based analysis of PDOs treated with drugs has not been realized in a high-throughput format due to the limited quantity of organoids. Here, we translated a newly developed poo...

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Detalles Bibliográficos
Autores principales: Wu, Yushuai, Li, Kaiyi, Li, Yaqian, Sun, Tao, Liu, Chang, Dong, Chunhui, Zhao, Tian, Tang, Decong, Chen, Xiaojie, Chen, Xiaofang, Liu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934649/
https://www.ncbi.nlm.nih.gov/pubmed/34893868
http://dx.doi.org/10.1093/nar/gkab1201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934649/
https://www.ncbi.nlm.nih.gov/pubmed/34893868
http://dx.doi.org/10.1093/nar/gkab1201

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