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Grouped-seq for integrated phenotypic and transcriptomic screening of patient-derived tumor organoids
Patient-derived tumor organoids (PDOs) have emerged as a reliable in vitro model for drug discovery. However, RNA sequencing-based analysis of PDOs treated with drugs has not been realized in a high-throughput format due to the limited quantity of organoids. Here, we translated a newly developed poo...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934649/ https://www.ncbi.nlm.nih.gov/pubmed/34893868 http://dx.doi.org/10.1093/nar/gkab1201 |