CMTR1 is recruited to transcription start sites and promotes ribosomal protein and histone gene expression in embryonic stem cells

CMTR1 (cap methyltransferase 1) catalyses methylation of the first transcribed nucleotide of RNAPII transcripts (N1 2′-O-Me), creating part of the mammalian RNA cap structure. In addition to marking RNA as self, N1 2′-O-Me has ill-defined roles in RNA expression and translation. Here, we investigate...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Shang, Silva, Joana C, Suska, Olga, Lukoszek, Radoslaw, Almohammed, Rajaei, Cowling, Victoria H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934662/
https://www.ncbi.nlm.nih.gov/pubmed/35212377
http://dx.doi.org/10.1093/nar/gkac122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934662/
https://www.ncbi.nlm.nih.gov/pubmed/35212377
http://dx.doi.org/10.1093/nar/gkac122

Ejemplares similares