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Extended sister-chromosome catenation leads to massive reorganization of the E. coli genome

In bacteria, chromosome segregation occurs progressively from the origin to terminus within minutes of replication of each locus. Between replication and segregation, sister loci are held in an apparent cohesive state by topological links. The decatenation activity of topoisomerase IV (Topo IV) is r...

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Detalles Bibliográficos
Autores principales: Conin, Brenna, Billault-Chaumartin, Ingrid, El Sayyed, Hafez, Quenech’Du, Nicole, Cockram, Charlotte, Koszul, Romain, Espéli, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934667/
https://www.ncbi.nlm.nih.gov/pubmed/35212387
http://dx.doi.org/10.1093/nar/gkac105