Multi-patient dose synthesis of [(18)F]Flumazenil via a copper-mediated (18)F-fluorination

BACKGROUND: Flumazenil (FMZ) is a functionally silent imidazobenzodiazepine which binds to the benzodiazepine binding site of approximately 75% of the brain γ-aminobutyric acid-A receptors (GABA(A)Rs). Positron Emission Tomography (PET) imaging of the GABAARs with [(11)C]FMZ has been used to evidenc...

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Detalles Bibliográficos
Autores principales: Gendron, Thibault, Destro, Gianluca, Straathof, Natan J. W., Sap, Jeroen B. I., Guibbal, Florian, Vriamont, Charles, Caygill, Claire, Atack, John R., Watkins, Andrew J., Marshall, Christopher, Hueting, Rebekka, Warnier, Corentin, Gouverneur, Véronique, Tredwell, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934836/
https://www.ncbi.nlm.nih.gov/pubmed/35306596
http://dx.doi.org/10.1186/s41181-022-00158-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934836/
https://www.ncbi.nlm.nih.gov/pubmed/35306596
http://dx.doi.org/10.1186/s41181-022-00158-z

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