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Feeder-Cell-Free and Serum-Free Expansion of Natural Killer Cells Using Cloudz Microspheres, G-Rex6M, and Human Platelet Lysate

The versatility of natural killer cells has ignited growing interest in their therapeutic use for cancer and other immunotherapy treatments. However, NK cells compose a small portion of peripheral blood mononuclear cells (5%–20% of PBMCs) and clinical doses require billions of cells. Manufacturing s...

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Detalles Bibliográficos
Autores principales: Johnson, Christopher D. L., Zale, Nicole E., Frary, Eric D., Lomakin, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934851/
https://www.ncbi.nlm.nih.gov/pubmed/35320938
http://dx.doi.org/10.3389/fimmu.2022.803380