Effect of the genetic mutant G71R in uridine diphosphate-glucuronosyltransferase 1A1 on the conjugation of bilirubin

We aimed to investigate the effect of the genetic mutant G71R (c. 211G > A) in uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1) on the glucuronidation of unconjugated bilirubin. The UGT1A1 wild-type and mutant G71R gene sequences were inserted into the lentiviral vector GV358 plasmi...

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Detalles Bibliográficos
Autores principales: Chen, Hong, Zhong, Danni, Gao, Zongyan, Wu, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934855/
https://www.ncbi.nlm.nih.gov/pubmed/35415244
http://dx.doi.org/10.1515/biol-2022-0021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934855/
https://www.ncbi.nlm.nih.gov/pubmed/35415244
http://dx.doi.org/10.1515/biol-2022-0021

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