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Effect of the genetic mutant G71R in uridine diphosphate-glucuronosyltransferase 1A1 on the conjugation of bilirubin

We aimed to investigate the effect of the genetic mutant G71R (c. 211G > A) in uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1) on the glucuronidation of unconjugated bilirubin. The UGT1A1 wild-type and mutant G71R gene sequences were inserted into the lentiviral vector GV358 plasmi...

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Detalles Bibliográficos
Autores principales:	Chen, Hong, Zhong, Danni, Gao, Zongyan, Wu, Xiaojing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934855/ https://www.ncbi.nlm.nih.gov/pubmed/35415244 http://dx.doi.org/10.1515/biol-2022-0021

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