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BAFF Blockade Attenuates DSS-Induced Chronic Colitis via Inhibiting NLRP3 Inflammasome and NF-κB Activation

BACKGROUND: BAFF production is increased in IBD patients. However, the specific role of BAFF in IBD is still uncovered. This study aimed to investigate the expression and function of BAFF in experimental colitis and the potential mechanisms. METHODS: BAFF levels in the serum and colon tissues were m...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Tao, Meihui, Chen, Chaoyue, Zhao, Xi, Feng, Qinyu, Chen, Guang, Fu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934862/
https://www.ncbi.nlm.nih.gov/pubmed/35320937
http://dx.doi.org/10.3389/fimmu.2022.783254