The DNMT1-PAS1-PH20 axis drives breast cancer growth and metastasis

PH20 is a member of the human hyaluronidase family that degrades hyaluronan in the extracellular matrix and controls tumor progression. Inhibition of DNA methyltransferases (DNMTs) leads to elevated hyaluronan levels; however, whether DNMT inhibitors control PH20 remains unclear. Here, we report tha...

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Detalles Bibliográficos
Autores principales: Fu, Yenan, Zhang, Xi, Liu, Xiao, Wang, Peng, Chu, Wenhui, Zhao, Wei, Wang, Yunling, Zhou, Guangbiao, Yu, Yu, Zhang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934873/
https://www.ncbi.nlm.nih.gov/pubmed/35307730
http://dx.doi.org/10.1038/s41392-022-00896-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934873/
https://www.ncbi.nlm.nih.gov/pubmed/35307730
http://dx.doi.org/10.1038/s41392-022-00896-1

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