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Mechanosensitive molecular mechanisms of myocardial fibrosis in living myocardial slices

AIMS: Altered mechanical load in response to injury is a main driver of myocardial interstitial fibrosis. No current in vitro model can precisely modulate mechanical load in a multicellular environment while maintaining physiological behaviour. Living myocardial slices (LMS) are a 300 μm‐thick cardi...

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Detalles Bibliográficos
Autores principales: Nunez‐Toldra, Raquel, Kirwin, Thomas, Ferraro, Elisa, Pitoulis, Fotios G., Nicastro, Laura, Bardi, Ifigeneia, Kit‐Anan, Worrapong, Gorelik, Julia, Simon, Andre R., Terracciano, Cesare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934971/
https://www.ncbi.nlm.nih.gov/pubmed/35128823
http://dx.doi.org/10.1002/ehf2.13832