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Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis

AIM: The acute phase of a coxsackievirus 3 (CVB3)‐induced myocarditis involves direct toxic cardiac effects and the systemic activation of the immune system, including the cardiosplenic axis. Consequently, the nucleotide‐binding oligomerization domain‐like receptor pyrin domain‐containing‐3 (NLRP3)...

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Detalles Bibliográficos
Autores principales: Pappritz, Kathleen, Lin, Jie, El‐Shafeey, Muhammad, Fechner, Henry, Kühl, Uwe, Alogna, Alessio, Spillmann, Frank, Elsanhoury, Ahmed, Schulz, Rainer, Tschöpe, Carsten, Van Linthout, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934990/
https://www.ncbi.nlm.nih.gov/pubmed/35178861
http://dx.doi.org/10.1002/ehf2.13845