Cargando…

Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis

AIM: The acute phase of a coxsackievirus 3 (CVB3)‐induced myocarditis involves direct toxic cardiac effects and the systemic activation of the immune system, including the cardiosplenic axis. Consequently, the nucleotide‐binding oligomerization domain‐like receptor pyrin domain‐containing‐3 (NLRP3)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pappritz, Kathleen, Lin, Jie, El‐Shafeey, Muhammad, Fechner, Henry, Kühl, Uwe, Alogna, Alessio, Spillmann, Frank, Elsanhoury, Ahmed, Schulz, Rainer, Tschöpe, Carsten, Van Linthout, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934990/ https://www.ncbi.nlm.nih.gov/pubmed/35178861 http://dx.doi.org/10.1002/ehf2.13845

Ejemplares similares

Sex- and age-related differences in the inflammatory properties of cardiac fibroblasts: impact on the cardiosplenic axis and cardiac fibrosis
por: Pappritz, Kathleen, et al.
Publicado: (2023)

Mesenchymal Stromal Cells Modulate Monocytes Trafficking in Coxsackievirus B3‐Induced Myocarditis
por: Miteva, Kapka, et al.
Publicado: (2017)

Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy
por: Miteva, Kapka, et al.
Publicado: (2018)

Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis
por: Tschöpe, Carsten, et al.
Publicado: (2020)

Targeting CD20+ B-lymphocytes in inflammatory dilated cardiomyopathy with rituximab improves clinical course: a case series
por: Tschöpe, Carsten, et al.
Publicado: (2019)

Telbivudine in chronic lymphocytic myocarditis and human parvovirus B19 transcriptional activity
por: Van Linthout, Sophie, et al.
Publicado: (2018)

The Spontaneous Course of Human Herpesvirus 6 DNA-Associated Myocarditis and the Effect of Immunosuppressive Intervention
por: Elsanhoury, Ahmed, et al.
Publicado: (2022)

CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis
por: Müller, Irene, et al.
Publicado: (2017)

Myeloid-Derived Suppressor Cells Restrain Natural Killer Cell Activity in Acute Coxsackievirus B3-Induced Myocarditis
por: Müller, Irene, et al.
Publicado: (2021)

A Toolbox of Potential Immune-Related Therapies for Inflammatory Cardiomyopathy
por: Elsanhoury, Ahmed, et al.
Publicado: (2020)

Characteristics of the Cardiosplenic Axis in Patients with Fatal Myocardial Infarction
por: Kercheva, Maria, et al.
Publicado: (2022)

The cardiosplenic axis: the prognostic role of the spleen in heart failure
por: Hiraiwa, Hiroaki, et al.
Publicado: (2022)

Viral myocarditis: a prime example for endomyocardial biopsy-guided diagnosis and therapy
por: Van Linthout, Sophie, et al.
Publicado: (2018)

Opioid-Induced Immunomodulation: Consequences for the Experimental Coxsackievirus B3-Induced Myocarditis Model
por: Pappritz, Kathleen, et al.
Publicado: (2020)

Epicardial Fat Expansion in Diabetic and Obese Patients With Heart Failure and Preserved Ejection Fraction—A Specific HFpEF Phenotype
por: Elsanhoury, Ahmed, et al.
Publicado: (2021)

Speckle-tracking echocardiography combined with imaging mass spectrometry assesses region-dependent alterations
por: Pappritz, Kathleen, et al.
Publicado: (2020)

SARS‐CoV‐2‐related myocarditis‐like syndromes Shakespeare's question: what's in a name?
por: Van Linthout, Sophie, et al.
Publicado: (2020)

Mechanical Unloading by Fulminant Myocarditis: LV-IMPELLA, ECMELLA, BI-PELLA, and PROPELLA Concepts
por: Tschöpe, Carsten, et al.
Publicado: (2018)

Reversible transition from a hypertrophic to a dilated cardiomyopathy
por: Spillmann, Frank, et al.
Publicado: (2015)

Colchicine for COVID-19: targeting NLRP3 inflammasome to blunt hyperinflammation
por: Bonaventura, Aldo, et al.
Publicado: (2022)

Colchicine reduces the activation of NLRP3 inflammasome in COVID-19 patients
por: Amaral, N. B., et al.
Publicado: (2023)

Serum alarmin S100A8/S100A9 levels and its potential role as biomarker in myocarditis
por: Müller, Irene, et al.
Publicado: (2020)

Cardiac (myo)fibroblasts modulate the migration of monocyte subsets
por: Pappritz, Kathleen, et al.
Publicado: (2018)

Impact of Syndecan-2-Selected Mesenchymal Stromal Cells on the Early Onset of Diabetic Cardiomyopathy in Diabetic db/db Mice
por: Pappritz, Kathleen, et al.
Publicado: (2021)

Mode-of-action of the PROPELLA concept in fulminant myocarditis
por: Spillmann, Frank, et al.
Publicado: (2019)

Treatment of Transthyretin Amyloid Cardiomyopathy: The Current Options, the Future, and the Challenges
por: Tschöpe, Carsten, et al.
Publicado: (2022)

Mesenchymal Stromal Cells but Not Cardiac Fibroblasts Exert Beneficial Systemic Immunomodulatory Effects in Experimental Myocarditis
por: Savvatis, Konstantinos, et al.
Publicado: (2012)

The CardioMEMS system in the clinical management of end-stage heart failure patients: three case reports
por: Tschöpe, Carsten, et al.
Publicado: (2018)

Case Report First-in-Man Method Description: Left Ventricular Unloading With iVAC2L During Veno-Arterial Extracorporeal Membrane Oxygenation: From Veno-Arterial Extracorporeal Membrane Oxygenation to ECMELLA to EC-iVAC®
por: Tschöpe, Carsten, et al.
Publicado: (2020)

The “TIDE”-Algorithm for the Weaning of Patients With Cardiogenic Shock and Temporarily Mechanical Left Ventricular Support With Impella Devices. A Cardiovascular Physiology-Based Approach
por: Tschöpe, Carsten, et al.
Publicado: (2021)

Colchicine prevents NSAID-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome
por: Otani, Koji, et al.
Publicado: (2016)

QRS fragmentation as a possible electrocardiographic diagnostic marker in patients with acute myocarditis: preliminary histopathological validation
por: Ferrero, Paolo, et al.
Publicado: (2020)

Colchicine Ameliorates Dilated Cardiomyopathy Via SIRT2‐Mediated Suppression of NLRP3 Inflammasome Activation
por: Sun, Xuan, et al.
Publicado: (2022)

Myocarditis and inflammatory cardiomyopathy: current evidence and future directions
por: Tschöpe, Carsten, et al.
Publicado: (2020)

New Echocardiographic Findings Correlate with Intramyocardial Inflammation in Endomyocardial Biopsies of Patients with Acute Myocarditis and Inflammatory Cardiomyopathy
por: Escher, Felicitas, et al.
Publicado: (2013)

Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction
por: Halade, Ganesh V., et al.
Publicado: (2016)

New Insights in (Inter)Cellular Mechanisms by Heart Failure with Preserved Ejection Fraction
por: Tschöpe, Carsten, et al.
Publicado: (2014)

Inflammation – Cause or Consequence of Heart Failure or Both?
por: Van Linthout, Sophie, et al.
Publicado: (2017)

Placenta‐Derived Adherent Stromal Cells Improve Diabetes Mellitus‐Associated Left Ventricular Diastolic Performance
por: Van Linthout, Sophie, et al.
Publicado: (2017)

Apolipoprotein A-I gene transfer exerts immunomodulatory effects and reduces vascular inflammation and fibrosis in ob/ob mice
por: Spillmann, Frank, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vm70vht6ib0313jn43q2khk9kt