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Pairs of Mutually Compensatory Frameshifting Mutations Contribute to Protein Evolution
Insertions and deletions of lengths not divisible by 3 in protein-coding sequences cause frameshifts that usually induce premature stop codons and may carry a high fitness cost. However, this cost can be partially offset by a second compensatory indel restoring the reading frame. The role of such pa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935012/ https://www.ncbi.nlm.nih.gov/pubmed/35137193 http://dx.doi.org/10.1093/molbev/msac031 |